徐有翠，副研究員、校聘副教授

研究方向：臟器（腎臟、肝臟）損傷炎性微環(huán)境的活體顯微成像分析、納米治療藥物開(kāi)發(fā)及機(jī)理解析；腫瘤及炎癥性疾病（臟器損傷、細(xì)菌感染等）診療納米藥物及新型疫苗系統(tǒng)的開(kāi)發(fā)

電子郵箱：xuyoucui@ahmu.edu.cn

辦公室：知行樓1215室

教育經(jīng)歷：

(1) 2015/09-2019/11， 中國(guó)科學(xué)技術(shù)大學(xué)，生命科學(xué)學(xué)院，博士（碩博連讀）

(2) 2011/09-2015/06， 安徽師范大學(xué)，生命科學(xué)學(xué)院，學(xué)士

工作經(jīng)歷：

(1) 2023/12至今，中國(guó)藥科大學(xué)，藥學(xué)院，副研究員，校聘副教授

(2) 2022/01-2023/12，廣東省人民醫(yī)院，博士后

(3) 2020/01-2022/01，中國(guó)科學(xué)技術(shù)大學(xué)附屬第一醫(yī)院，博士后

科研項(xiàng)目：

（1）中國(guó)博士后科學(xué)基金特別資助項(xiàng)目，2023T160136，基于微轉(zhuǎn)移灶特異性蛋白和原位白蛋白劫持的熒光探針用于微轉(zhuǎn)移灶的近紅外二區(qū)高分辨成像，2023-01至2023-12，18萬(wàn)元，結(jié)題，主持

發(fā)表論文情況：

1. Xu Y, Chen J*, JiangW,ZhaoY,YangC, WuY,LiQ,Zhu C*. Multiplexing NanodrugAmelioratesLiver Fibrosis via ROS Elimination and Inflammation Suppression.Small, 2022, e2102848. [IF:13.3，中科院一區(qū)，TOP期刊]

2. Xu Y#,YangC#, WuY,JiangW,ChengQ,YanL, Chen K*,WangY*. In SituAlbumin-hitchhikingNIR-IIProbesforAccurateDetectionofMicrometastases.NanoLetters,2023,23,5731-5737. [IF:10.8，中科院一區(qū)，TOP期刊]

3.XuY#,WuY#,HuY#,XuM,LiuY,DingY,ChenJ,HuangX,WenLP*,LiJ*&ZhuC*.Bacteria-basedMultiplexSystemEradicatesRecurrentInfection with Drug-resistant Bacteria via Photothermal Killing and Protective Immunity Elicitation.Biomaterials Research,2023, 27,27. [IF:11.3，中科院一區(qū)]

4. Chen J#*, Zhang X, Zhang J, Wang Z, Zhu G, Geng M, Zhu J, Chen Y, Wang W*,Xu Y*. Multifunctional Responsive Hydrogel System for Synergistic Reoxygenation and Chemo/Photothermal Therapy of Metastatic Breast Cancer and Wound Infection.Journal of Controlled Release, 2024, 365,74-88. [IF:10.8，中科院一區(qū)，TOP期刊]

5.  Zhang W#,WeiP#,Liu L#, Ding T, Yang Y, Jin P, Zhang L, Zhao Z, Wang M, Hu B, Jin X, Xu Z, Zhang H, Song Y, Wang L, Zhong S, Chen J, Yang Z, Chen Z, Wu Y, Ye Z,XuY*,ZhangY*&WenLP*.AIE-enabled Transfection-free Identification and Isolation of Viable Cell Subpopulations Differing in the Level of Autophagy.Autophagy,2023, 19, 3062-3078. [IF:13.3，中科院一區(qū)，TOP期刊]

6. Xie C#,Xu Y#, Liu Y, Chen M, Du P, Zhang Y*, Ma X*, Yang S*. Edge-Selective Covalent Passivation of Black Phosphorus Nanosheets by Fullerene C70 toward Enhanced Antimicrobial Performance [J]. Chemical Engineering Journal, 2023, 477, 146997.[IF:15.1，中科院一區(qū)，TOP期刊]

7.  Zhong S#, Zhong S#, Wu Y#, Liu Z, Yang Y, Wang X, Li S, Wu Y, Huang X, Zhu Y, Zhou Z,Xu Y*, Wen L*, Yao X*. Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3.Journal of Controlled Release, 2025, 380, 417-432. [IF:10.8，中科院一區(qū)，TOP期刊]

8.  Odda A H#,Xu Y#, Lin J*,WangG, Ullah N, Zeb A, Liang K,WenLP*, XuAW*.PlasmonicMoO3?xNanoparticlesIncorporatedinPrussianBlue FrameworksExhibitHighlyEfficient Dual Photothermal/PhotodynamicTherapy.JournalofMaterialsChemistryB,2019,7,2032-2042. [IF:7.0，中科院二區(qū)，TOP期刊]

9. Huang X#, Cao Z#, Qian J#, Ding T, Wu Y, Zhang H, Zhong S, Wang X, Ren X, Zhang W,Xu Y, Yao G, Wang X, Wen LP*, Yang X*, Zhang Y*. Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors.Nature Nanotechnology, 2024, 19, 545-553. [IF:38.3，中科院一區(qū)，TOP期刊]

10.  Wu Y#, Jiang W#, Huo S#, Li S,Xu Y, Ding S, ZhouJ,Liu H,LvW*,WangY*.Nano-metal-organic-frameworks for Treating H2O2-Secreting Bacteria Alleviate Pulmonary Injury and Prevent Systemic Sepsis.Biomaterials, 2021, 279, 121237. [IF:14.0，中科院一區(qū)，TOP期刊]

11.  Wang L#, Zhong S#, Fan X, Xu Y, Wang M,Xu Y, Cai Y, Cao Z, Ye Z*, Wen L*, Wei P*. Glutathione reductase underlies the stability of mutant p53 by antagonizing protein glutathionylation. Redox Biology, 2025, 81, 103522. [IF:10.7，中科院一區(qū)，TOP期刊]

12.  Zhu Y#, Zhang H#, Mao H#, Zhong S, HuangY,Chen S,YanK, Zhao Z, HaoX,ZhangY,YaoH, HuangX,WangM,ZhangW,LiJ,MengG,QinX,YeZ,ShenJ,SongY,XuY,YangZ,WangL*,ZhangY*,WenL*.FAAHServed a Key Membrane-Anchoring and StabilizingRolefor NLRP3 ProteinIndependently of the Endocannabinoid System.Cell Death & Differentiation, 2023,30, 168-183. [IF:12.4，中科院一區(qū)，TOP期刊]

13.  Ma Y#,TangX#,Xu Y, JiangW,XinY,ZhaoW,HeX,LuL*,Zhan M*. Nano-enabledCoordinationPlatform of Bismuth Nitrate and Cisplatin Prodrug Potentiates Cancer Chemoradiotherapy via DNA Damage Enhancement.Biomaterials Science, 2021, 9, 3401-3409. [IF:6.6，中科院二區(qū)]

14.  YaoH, ZhangY,Liu, L,Xu Y, LiuX,LinJ,ZhouW,WeiP,JinP,WenLP*. InhibitionofLanthanideNanocrystal-induced Inflammasome Activation in Macrophages by a Surface Coating Peptide Through Abrogation of ROS Production and TRPM2-Mediated Ca2+Influx.Biomaterials, 2016, 108, 143-156. [IF:12.4，中科院一區(qū)，TOP期刊]