陳巖，校聘副教授

研究方向：抗炎活性導(dǎo)向的藥用植物微生物來源新穎結(jié)構(gòu)天然產(chǎn)物的發(fā)現(xiàn)及在炎癥疾病中的功能研究

電子郵箱：cychemistry@163.com

辦公室：知行樓B1111

教育經(jīng)歷：

(1) 2017/09-2020/06， 中山大學(xué)，海洋科學(xué)學(xué)院，博士

(2) 2015/09-2017/06， 中山大學(xué)，化學(xué)院，碩士

工作經(jīng)歷：

(1) 2022/08至今，安徽醫(yī)科大學(xué)，藥學(xué)科學(xué)院，校聘教授

(2) 2020/07-2022/07，河南大學(xué)，藥學(xué)院，師資博后

主持課題項目情況：

（1）安徽省高校自然科學(xué)科研項目：2022AH050706，主持

（2）安徽省自然科學(xué)基金青年項目：2308085QH302，主持

發(fā)表論文情況：

1. Guisheng Wang, Zhaokun Li, Jianying Wu, Wencong Yang, Hang Li, Jiyan Pang, Zhigang She,* and Yan Chen*. Mining of Meroterpenoids with Anti-inflammatory Activity from the Mangrove Endophytic Fungus Talaromyces sp. JNQQJ 4 by Genome Analysis and Molecular Network Strategy. Org. Lett. 2025, 27, 1662?1667.

2. Yan Chen, Wencong Yang, Ge Zhu, Guisheng Wang, Tao Chen, Hang Li, Jie Yuan,* Zhigang She*. Didymorenloids A–B, two polycyclic cyclopenta[b] fluorene-type alkaloids with anti-hepatoma activity from the mangrove endophytic fungus Didymella sp. CYSK-4. Org. Chem. Front., 2024,11, 1706

3. Guisheng Wang, Yilin Yuan, Zhaokun Li, Xuguang Liu, Yanhai Chu, Zhigang She,* Wenyi Kang* and Yan Chen*. Pleosmaranes A-R, Isopimarane and 20-nor Isopimarane Diterpenoids with Anti-inflammatory Activities from the Mangrove Endophytic Fungus Pleosporales sp. HNQQJ-1. J. Nat. Prod. 2024, 87, 304-314.

4. Yan Chen, Wencong Yang, Ge Zou, Guisheng Wang, Wenyi Kang, Jie Yuan*, Zhigang She*. Cytotoxic Bromine- and Iodine-Containing Cytochalasins Produced by the Mangrove Endophytic Fungus Phomopsis sp. QYM-13 Using the OSMAC Approach. Journal of Natural Products 2022, 85, 1229-1238.

5. Yan Chen, Hongju Liu, Wencong Yang, Lishan Zhang, Ge Zou, Changqun Li, Zhangyuan Yan, Yuhua Long and Zhigang She*. Bioactive Sesquiterpene Derivatives from Mangrove Endophytic fungus Phomopsis sp. SYSU-QYP-23: Structures and Nitric Oxide Inhibitory Activities. Bioorganic Chemistry 2021, 107, 104530.

發(fā)表專利情況：

（1）陳巖，李兆昆，朱君豪。一種紅樹內(nèi)生真菌中具有抗炎活性的異香豆素類化合物及其制備方法和應(yīng)用。202411020596.1。