陳向濤，副教授

研究方向：中藥及活性成分改善學(xué)習(xí)記憶的研究

電子郵箱：陳向濤@ahmu.edu.cn

辦公室：知行樓B1206

教育經(jīng)歷：

(1) 2001/09-2005/06， 安徽醫(yī)科大學(xué)，藥學(xué)院，博士

(2) 1992/09-1995/06， 安徽中醫(yī)藥大學(xué)，中醫(yī)臨床學(xué)院，碩士

(3)1987/09-1992/06，  安徽中醫(yī)藥大學(xué)，中醫(yī)臨床學(xué)院，學(xué)士

工作經(jīng)歷：

(1) 2013/07至今，安徽醫(yī)科大學(xué)，藥學(xué)院，副教授

(2) 2008/09-2011/09，美國(guó)加州大學(xué)伯克利，分子與遺傳學(xué)院，訪問(wèn)學(xué)者

(3) 2006/04-2008/08，中國(guó)科學(xué)技術(shù)大學(xué)， 生命科學(xué)學(xué)院， 博士后

(4) 1995/07-2013/08 安徽中醫(yī)藥大學(xué)，教師

科研項(xiàng)目：

(1)國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目, 82274124, “芳香開(kāi)竅”中藥石菖蒲改善學(xué)習(xí)記憶功能的內(nèi)嗅皮層-海馬神經(jīng)環(huán)路機(jī)制研究, 2023-01-01至2026-12-31, 52萬(wàn)元,在研,主持

(2)國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目, 81673624, β-細(xì)辛醚通過(guò)調(diào)控NMDA受體興奮性和突觸重塑抗阿爾茨海默病的作用機(jī)制研究, 2017.01至2020.12, 52萬(wàn)元,已結(jié)題,主持

發(fā)表論文情況：

1.Lanxiang Yin, Xintong Yuan, Jiahui Yu, Xuemin Ren, Hongqin Zhan, Yunyan Ye, Zixuan Wang, Xiangtao Chen#, β-asarone relieves Parkinson's disease through reducing intracellular Ca2+ in PINK1 mutant Drosophila melanogaster [J].Eur J Pharmacol, 2025 15:987:177155

2.Yanyan Xiao, Chenglin Yang, Nana Si, Tao Chu, Jiahui Yu, Xintong Yuan, Xiang-Tao Chen#. Epigallocatechin-3-gallate Inhibits LPS/AβO-induced Neuroinflammation in BV2 Cells through Regulating the ROS/TXNIP/NLRP3 Pathway [J]. Journal of Neuroimmune Pharmacology, 2024, 19(1): 31.

3.Rong-Xin Zou, Xiaozhen Gu, Chenqing Huang, Hui-Li Wang, Xiang-Tao Chen#. Pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice [J]. Toxicology, 2024, 502: 153717.

4.Juanjuan Liu, Xiaozhen Gu, Rongxin Zou, Wenping Nan, Shaohua Yang, Hui-Li Wang, Xiang-Tao Chen#. Phytohormone abscisic acid improves spatial memory and synaptogenesis involving NDR1/2 kinase in rats [J]. Frontiers in pharmacology, 2018, 9: 1141.

5.Haoyu Liu, Ruiqing Zhou, Lanxiang Yin, Nana Si, Chenglin Yang, Chengqing Huang, Rongrong Wang, Xiangtao Chen#. β-asarone prolongs sleep via regulating the level of glutamate in the PVN [J]. Biochemical and Biophysical Research Communications, 2023, 665: 71-7.

6.Shu Ai, Danyang Li, Xiaozhen Gu, Yi Xu, Yi Wang, Hui-Li Wang, Xiang-Tao Chen. Profile of N6-methyladenosine of Pb-exposed neurons presents epitranscriptomic alterations in PI3K-AKT pathway-associated genes [J]. Food and Chemical Toxicology, 2023, 178: 113821.

7.Rong-Xin Zou, Xiaozhen Gu, Jin-Jun Ding, Tiandong Wang, Nanxi Bi, Kang Niu, Mengmeng Ge, Xiang-Tao Chen#, Hui-Li Wang#. Pb exposure induces an imbalance of excitatory and inhibitory synaptic transmission in cultured rat hippocampal neurons [J]. Toxicology in Vitro, 2020, 63: 104742.

8.Ruiqing Zhou, Jing Zhao, Danyang Li, Yao Chen, Yanyan Xiao, Anni Fan, Xiang-Tao Chen#, Hui-Li Wang#. Combined exposure of lead and cadmium leads to the aggravated neurotoxicity through regulating the expression of histone deacetylase 2 [J]. Chemosphere, 2020, 252: 126589.